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Cellular mesoblastic nephroma

Congenital mesoblastic nephroma (CMN) is the most common renal tumor in the first year of life. Here, we present unique findings of cellular variant CMN seen on prenatal and postnatal MRI with diffusion-weighted imaging (DWI).The mass was well-visualized on prenatal MR DWI with diffusion restriction in the solid portions Mesoblastic nephroma, also sometimes known as a congenital mesoblastic nephroma (CMN) or fetal renal hamartoma, is, in general, a benign renal tumor that typically occurs in utero or in infancy Axial CECT in a patient with cellular mesoblastic nephroma shows a crescent of residual right kidney splayed along the posterior margin of the heterogeneous mass. This claw sign helps to identify the kidney as the organ of origin for the tumor. Sign in to download full-size imag Clear cell sarcoma, cellular mesoblastic nephroma and metanephric adenoma: cytological features and differential diagnosis with Wilms tumour Cytopathology. 2008 Apr;19(2):80-5. doi: 10.1111/j.1365-2303.2007.00460.x. Epub 2007 Aug 6. Authors R Portugal 1.

Comments: Cellular (atypical) mesoblastic nephroma consists of a highly cellular proliferation of atypical spindle cells with brisk mitotic activity. The appearance is similar to that of infantile fibrosarcoma Cellular CMN May be more cellular than the classical form of mesoblastic nephroma (image C). Cells may be polygonal or spindled. Margins may appear to be more pushing than infiltrative

Cellular Mesoblastic Nephroma with Liver Metastasis in a

  1. Mesoblastic nephroma, cellular type, stage II (due to renal sinus and perirenal fat invasion) (see comment) Comment: Tumor shows dense cellularity with plump cells with vesicular nuclei and with a high mitotic activity. Tumor is infiltrating the renal sinus and perirenal fat but is not reaching the resection margins. Lymph nodes are free of tumor
  2. Cellular mesoblastic nephroma in infants and children: Report of four cases and review of the literature - Bita Geramizadeh, Ali Kashkooe, Pedram Keshavarz, Soheila Zareifar, Hamidreza Foroutan, 2020 Skip to main content Intended for healthcare professional
  3. ation of these tumors provides critical information on their prognoses. This exa
  4. Congenital mesoblastic nephroma (CMN) is a rare renal tumor of early infancy with a favorable outcome after complete surgical removal. CMN consists of a heterogeneous group of spindle cell tumors subdivided into classical, cellular or atypical and mixed forms based on histologic features

Congenital mesoblastic nephroma (CMN) is the most commonly occurring renal tumor in the first year of life. It was originally described by Bolande et al. [ 1] as a leiomyoma-like tumor with excellent prognosis with nephrectomy alone Cellular mesoblastic nephroma: morphologic, cytogenetic and molecular links with congenital fibrosarcoma. Henno S, Loeuillet L, Henry C, D'Hervé D, Azzis O, Ferrer J, Poulain P, Babut JM, Merlio JP, Jouan H, Dubus P Pathol Res Pract 2003;199(1):35-40. doi: 10.1078/0344-0338-00350 Cellular mesoblastic nephroma Final Diagnosis. Cellular mesoblastic nephroma References [1] Murthi GV, Carachi R, Howatson A. Congenital cystic mesoblastic nephroma. Pediatr Surg Int 2003; 19: 109-111. (PMID: 12721740) [2] Irsutti M, Puget C, Baunin C et al.. Congenital mesoblastic nephroma (CMN) is an uncommon tumour in the neonatal period. Many CMNs are of typical histology and require no therapy other than nephrectomy. However, some are of atypical histology and are known to recur and metastasize Fine‐needle aspiration smears consisted of a few cellular clusters of spindle cells with mitotic activity and mild nuclear pleomorphism. No blastema was identified. A cytologic impression of mesoblastic nephroma was rendered, which was confirmed on histopathological examination of the right nephrectomy specimen as a cellular mesoblastic nephroma

Congenital mesoblastic nephroma (CMN) is a mesenchymal renal tumor that was distinguished from Wilms' tumor (WT) in 1967 (1). CMN is the most frequent type of renal tumor in the neonatal and early infantile period, comprising 3-10% of all childhood renal tumors Cellular mesoblastic nephroma is a rare but aggressive congenital renal tumor. The index of suspicion should be high in a patient who presents in the neonatal period with a renal mass, especially in the presence of gestational polyhydramnios Congenital mesoblastic nephroma (CMN) was first described in 1967 by Bolande et al. as a leiomyoma-like tumor of the kidney.It is the most commonly occurring renal tumor found in infants less than three months old, and known to have a favorable outcome after complete surgical excision ().Joshi et al. summarized the main pathological variants of CMN as the classic variant and cellular variant

INTRODUCTION: Congenital Mesoblastic Nephroma (CMN) is a rare pediatric renal tumor. It comprises two histological subtypes, namely classic and cellular, with the second accounting for two thirds of all cases and being more often associated with poor prognosis. It remains a diagnostic challenge for pathologists due to its similarity with other more frequent pediatric kidney neoplasms Cellular mesoblastic nephroma in a female neonate. F-I. Whole body MRI during follow-up shows huge cystic recurrent mass (arrows) in left retroperitoneum on T2-weighted image (F) with liver dome mass (arrow), appearing as high signal on T2-weighted image (G) and diffusion restriction on diffusion-weighted imaging (H) an BACKGROUND: Cellular mesoblastic nephroma has been associated with a more aggressive course than classic mesoblastic nephroma, including local recurrences and metastases. OBJECTIVE: To define the clinicopathologic and imaging features distinguishing cellular from classic mesoblastic nephroma Congenital mesoblastic nephroma (CMN) is the most common renal tumor in neonates and infants less thansix months of age. CMN may be identified on prenatal ultrasound. More commonly, infants present with an abdominal mass. Paraneoplastic syndromes such as hypertension or hypercalcemia are possible Bayindir P, Guillerman RP, Hicks MJ, Chintagumpala MM. Cellular mesoblastic nephroma (infantile renal fibrosarcoma): institutional review of the clinical, diagnostic imaging, and pathologic features of a distinctive neoplasm of infancy. Pediatr Radiol. 2009 Oct. 39(10):1066-74. . Do AY, Kim JS, Choi SJ, Oh SY, Roh CR, Kim JH

Mesoblastic nephroma Radiology Reference Article

Mesoblastic Nephroma - an overview ScienceDirect Topic

Clear cell sarcoma, cellular mesoblastic nephroma and

Among the low-grade malignant tumors congenital mesoblastic nephroma can be successfully treated with simple nephrectomy. 3 There, are however, variants of CMN which may differ in clinical behavior from the typical form of CMN. These variants include the cellular CMN2 and, possibly, the malignant mesenchymal nephroma of in fancy6 Aims. Congenital mesoblastic nephroma (CMN) is histologically classified into classic, cellular and mixed subtypes. The aims of this study were to characterise the clinical, pathological and molecular features of a series of CMNs, and to determine the utility of pan-Trk and epidermal growth factor receptor (EGFR) immunohistochemistry as surrogate markers for NTRK gene fusions and EGFR internal. Diagnosis: Congenital mesoblastic nephroma (classic) Congenital renal tumors comprise 2.5-7% of all perinatal tumors. Congenital renal neoplasms include, in decreasing order of frequency, congenital mesoblastic nephroma, Wilms tumor, rhabdoid tumor, clear cell sarcoma, hamartomas, and ossifying tumor of infancy A case of partially cystic atypical or cellular variant of mesoblastic nephroma in a 27 year old woman is reported herein. Some of the cysts were like those seen in a cystic nephroma (solitary multilocular cyst) and others resembled ectasic vascular channels. Nephrectomy was the only treatment used Sixteen cases of congenital mesoblastic nephroma (CMN) were studied. The tumors showed variable patterns of growth, degrees of cellularity, and mitotic activity. Six tumors had the classical pattern of CMN, seven were of the cellular or atypical variant and three showed combined features. The mean ages at presentation were 16 days, 5.3 months, and 2.3 months, respectively

Mesoblastic Nephroma - Cellular pattern - WebPatholog

Congenital Mesoblastic Nephroma - American Urological

Congenital mesoblastic nephroma represents 3% of all pediatric kidney tumors [].It is the most common kidney neoplasm diagnosed in the first 3 months of life, and it is frequently detected antenatally, as described in our case [].The malignant potential of the tumor is low Fetal congenital mesoblastic nephroma (CMN) is a rare renal tumor, characterized by polyhydramnios, premature birth, and neonatal hypertension. In the prenatal stage, it is particularly difficult to diagnose CMN either by ultrasonography or magnetic resonance imaging (MRI). Thus, CMN is frequently detected in the third trimester in the clinical. Cellular. Features: Plump cells with vesicular nuclei. Well-defined border. Mitotically active. Mixed. Like the name implies - both classic pattern and cellular pattern areas are present. Molecular. Cellular mesoblastic nephroma: t(12:15)(p13;q25) ETV6/NTRK3. Same translocation if found in infantile fibrosarcoma. Clear cell sarcoma of the kidne Cytogenetic and molecular analyses were performed on three cellular (atypical) congenital mesoblastic nephromas (CMNs). Two cases had trisomy 11; in one, it was the sole karyotypic abnormality, and the other had additional numerical changes as well as an isochromosome for the long arm of chromosome I. Markers for the 11p13 and 11p15 loci were present in three copies in these two CMNs

Pathology Outlines - Congenital mesoblastic nephroma

Pathology Outlines - Congenital mesoblastic nephrom

Congenital mesoblastic nephroma is the most common renal mass in the newborn period and can present with atypical findings. Certain associated conditions such as hypercalcaemia, hypertension and reninism have been described. Fingerprint Dive into the research topics of 'Cellular congenital mesoblastic nephroma with contralateral medullary. Additionally, lamin A/C (LMNA)-NTRK1 fusion has been infrequently reported in congenital infantile fibrosarcoma [4, 16,17,18], cellular mesoblastic nephroma , and lipofibromatosis-like neural tumors . We have recently encountered pediatric cases of intracranial and forehead sarcomas

Cellular mesoblastic nephroma can have greater degrees of cellularity and cytologic atypia potentially resembling CCSK, and definitive diagnosis then rests on identification of the ETV6-NTRK3 or variant gene fusions. BCOR immunohistochemistry, if positive, can support a diagnosis of CCSK but, as discussed above, lacks sensitivity and specificity Aim: Congenital mesoblastic nephroma (CMN) is the commonest renal tumour of infancy, with classical, cellular and mixed histological subtypes described. A specific ETV6‐NTRK3 fusion‐gene product is reported in association with the cellular variant. The aim was to investigate the relationship between the presence of this product and morphological phenotype using paraffin‐embedded archival. Congenital mesoblastic nephroma, while rare, is the most common kidney neoplasm diagnosed in the first three months of life and accounts for 3-5% of all childhood renal neoplasms. [1] [2] This neoplasm is generally non-aggressive and amenable to surgical removal. However, a readily identifiable subset of these kidney tumors has a more malignant potential and is capable of causing life. Congenital mesoblastic nephroma (CMN) is the most common renal solid tumor of the newborn period ().CMN occurs in two forms: a typical or leiomyomatous benign type seen almost exclusively in infants under the age of three months and an atypical or cellular type usually seen in older children, but also occurring in infants Congenital mesoblastic nephroma, while rare, is the most common kidney neoplasm diagnosed in the first three months of life and accounts for 3-5% of all childhood renal neoplasms. This neoplasm is generally non-aggressive and amenable to surgical removal. However, a readily identifiable subset of these kidney tumors has a more malignant potential and is capable of causing life-threatening.

Mesoblastic nephroma - Wikipedi

mesoblastic: ( mez'ō-blas'tik ), Relating to or derived from the mesoderm The most common malignant renal tumors of childhood are Wilms tumor (WT), clear cell sarcoma of the kidney (CCSK), cellular mesoblastic nephroma (CMN), and rhabdoid tumor of the kidney (RTK). Because these tumors present significant diagnostic difficulties, the goal was to define diagnostically useful signatures based on gene expression Overall, tumors of the kidney are rare, with mesoblastic nephroma the most commonly detected. This tumor arises exclusively in the third trimester and demonstrates rapid growth. 5 Genetic Evaluation If a duplicated collecting system is seen as an isolated anomaly and the family history is unremarkable, the chance of a genetic syndrome is low

Cellular Mesoblastic Nephroma: Morphologic, Cytogenetic

Imaging of congenital mesoblastic nephroma with

Advanced Imaging Research Center (AIRC) Cecil H. and Ida Green Comprehensive Center for Molecular, Computational, and Systems Biology; Cecil H. and Ida Green Center for Reproductive Biology Science 52 Cellular Mesoblastic Nephroma Surgical Pathology No. SP 08-6 (SP-358) We describe a 7-month-old male with an abdominal mass diagnosed as mesoblastic nephroma. Computed tomographic scan of a unilateral, firm, fixed mass showed a heterogeneous mass in the upper quadrant of the left kidney extending to the pelvis compatible with a Wilms.

Mesoblastic nephroma, cellular (Concept Id: C1320471

Congenital mesoblastic nephroma is the most common renal mass in the newborn period and can present with atypical findings. Certain associated conditions such as hypercalcaemia, hypertension and reninism have been described Mesoblastic nephroma (MN) is the most frequent renal neoplasm of newborns and young infants. 1-3 In 1967, Bolande et al. defined congenital mesoblastic nephroma as an entity that differs from nephroblastoma. 3 The tumor is characterized by leiomyomatous histology with spindled cells in bundles, rare mitoses, and the absence of necrosis. Because. Fig. 4 Cellular mesoblastic nephroma. Note closely packed plump cells & mitotic figures (H&E ×400). commoner than classic mesoblastic nephroma with a ratio of 3:1, and that the former presents a few months later in life than the lat-ter [5]. Unlike the classic type, cellular mesoblastic nephroma may reach a huge size and can weigh more than 1kg

congenital mesoblastic nephroma is not a nephroma at all and most likely represents a soft-tissue tumour. They also surmised that congenital infantile fibrosarcoma repre-sented a cellular congenital mesoblastic nephroma with a predilection to arise in the kidney. Numerous other studies in both adult and paediatri Mesoblastic nephroma has three variants: classic/leiomyomatous, cellular/atypical, and mixed variants. The cellular variant has a 5-year survival rate of 85% and an overall survival rate of 90% [ 3 ]

classified as a cellular mesoblastic nephroma (Fig. 5). The neonate's karyotype was normal (46, XX). DISCUSSION CMN is the most common renal tumor in infancy, account-ing for 3-6% of all childhood renal masses and 50% of all solid tumors in the neonatal period (13). Current opinion favors the classification of mesoblastic nephroma as a distinct Congenital mesoblastic nephroma is the most common renal neoplasm in newborns and in early infancy. Of patients presented in a series of 50 cases, 74% of the patients were younger than four months of age. 1 Traditional thinking is that congenital mesoblastic nephroma is a surgically cured benign disease and neoadjuvant or adjuvant therapy has little to offer Congenital mesoblastic nephroma is a rare tumour of infancy comprising 3-6% of renal masses in childhood and 50% of renal masses during the neonatal period [].A total of 19-50% of mesoblastic nephromas will have cellular elements on histology [2, 3].However, the majority of mesoblastic nephromas are of the classic type which consists of fascicles and bundles of myofibroblasts in the tumour A diagnosis of cellular mesoblastic nephroma was made on the basis of cellular characteristics, growth pattern and mitosis. No epithelial and blastemal component was noted even after extensive sampling of the tumour. No postoperative chemotherapy was administered and there was no relapse even after 2 years of follow-up Data from the National Wilms Tumor Study show that cellular mesoblastic nephroma is more common than classic mesoblastic nephroma by almost 3 to 1, and that cellular mesoblastic nephroma presents a few months later in life than classic mesoblastic nephroma.3 Cellular mesoblastic nephromas may grow to be large and can weigh more than 1 kg, while.

Congenital mesoblastic nephroma is one of the commonestkidney tumours in infants. It has been associated with a very good prog-nosis and, in most cases, surgery alone may effectacure.' It has also been recognised, however, that notall ofthecasesfollowthesamecourse.24A more aggressive subtype, atypical cellular mesoblastic nephroma with evidence. Read Cellular mesoblastic nephroma (infantile renal fibrosarcoma): institutional review of the clinical, diagnostic imaging, and pathologic features of a distinctive neoplasm of infancy, Pediatric Radiology on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips

Molecular: ETV6-NTRK3 fusions (also seen in cellular mesoblastic nephroma) Almost defined out of existence -Dr. Richard Kempson (Many tumors previously called fibrosarcoma have been re-classified as synovial sarcoma, UPS, fibromatosis, or MPNST) Now a diagnosis of exclusion! Must do work up to exclude other diagnoses (IHC and FISH) Like infantile fibrosarcoma, cellular congenital mesoblastic nephroma typically harbors the ETV6-NTRK3 rearrangement. 17, 18 The ETV6-NTRK3 fusion has also been shown to be oncogenic in. Cellular congenital mesoblastic nephroma in a newborn. Schmidt D, Harms D, Lehner-Geisser M. Pathol Res Pract 1984 Nov;179(2):242-9 Abstract quote Typical nephroblastoma (Wilms'tumor) is uncommon within the first 6 months of life. Renal tumors most commonly found in this age constitute of two groups which have a better and worse prognosis. A detailed ultrastructural description of the cellular variant of congenital mesoblastic nephroma (CMN) is presented and compared to the classical form. Studied were 9 cases of the cellular variant, 6 mixed (cellular/classical) tumors, and 1 classical CMN Congenital mesoblastic nephroma (CMN) is a mesenchymal renal tumor. The aim of the present study was to review the clinical characteristics and outcome of CMN in infants. A retrospective file review was conducted of eight cases of CMN treated at the Children's Hospital of Fudan University between 2004 and 2012. Ultrasound and computerized tomography scans had been performed on all eight patients

Cellular mesoblastic nephroma. Secretory carcinoma. t(12;15)(p13;q25) NTRK FUSIONS ACROSS TUMOR TYPES. High frequency in special histologic types. Low frequency in common forms of different types of cancers • Secretory breast carcinoma • Mammary analogue secretory carcinoma of th ETV6-NTRK3Congenital fibrosarcoma/cellular mesoblastic nephroma fusion [t(12;15)(p13;q25)] Solid Tumor Fusion Analysis by NGS [test code: TUMFUSN] Identifies gene fusions for 111 genes (see website for list of all gene partners). *At least 10% tumor must be present in the submitted Fresh, Snap-frozen, OCT, or Bone marrow tumor samples Cellular mesoblastic nephroma histologically looks like densely packed spindle cells with a high mitotic rate, which appear sarcomatous, but may also show a mixture of cellular and classic mesoblastic nephroma patterns. Data from the National Wilms Tumor Study show that cellular mesoblastic nephroma is more common than classic mesoblastic. Mesoblastic nephroma is a benign mesenchymal tumor of the kidney generally diagnosed during the first 3 months of life. A case of the cellular variant of mesoblastic nephroma associated with promin.. Cellular mesoblastic nephroma has been shown to be Discussion associated with Tel-ETV6/Trk-NTRK3 fusion transcript as a consequence of a cryptic translocation [t(12; 15) (p13; q25)] Paediatric renal neoplasms present special challenges to [11]. A possible link of cellular mesoblastic nephroma with surgical pathologists because they are often.

Less common types of childhood kidney tumors include rhabdoid tumors, clear cell sarcoma, congenital mesoblastic nephroma, Ewing sarcoma of the kidney, primary renal myoepithelial carcinoma, cystic partially differentiated nephroblastoma, multilocular cystic nephroma, primary renal synovial sarcoma, and anaplastic sarcoma Mesoblastic nephroma: Negative for ER and PR; t(12;15)(p13;q25), resulting in ETV6-NTRK3 gene fusion, seen in cellular type Multilocular cystic neoplasm of low malignant potential: Clusters or nests of clear cells present in cystic septa No cellular strom

Analysis of mixed mesoblastic nephromas for ETV6-NTRK3

Cellular Mesoblastic Nephroma Eurora

Congenital fibrosarcoma (CFS) and cellular mesoblastic nephroma (CMN) are pediatric spindle cell malignancies that share two specific cytogenetic abnormalities: trisomy of chromosome 11 and a t(12. mesoblastic nephroma: a spindle cell neoplasm of the infant and, rarely, adult kidney with entrapped renal tubules Cellular mesoblastic nephroma in an infant: report of the cytologic diagnosis of a rare paediatric renal tumor. Diagn Cytopathol 2009 ; 37 : 377 - 380 . Argani , P , Perlman , EJ , Breslow , NE , et al Mesoblastic nephroma (MN) is the most common renal tumor diagnosed in infancy. A case of congenital MN was diagnosed in a 6‐month old child by fine‐needle aspiration cytology. The smears were cellular and consisted of plump spindle cells arranged in clusters along with scattered naked nuclei in the background. Blastemal, epithelial, or glomeruloid structures were not seen Geralmente, a recorrência ocorre no primeiro ano de tratamento, principalmente quando o subtipo é o celular.<br>INTRODUCTION: Congenital Mesoblastic Nephroma (CMN) is a rare pediatric renal tumor. It comprises two histological subtypes, namely classic and cellular, with the second accounting for two thirds of all cases and being more often.

Cellular mesoblastic nephroma tends to present later in infanc than the classic formy, and can exhibit aggressive behavior including metastases (Bayindir et al., 2009). It has been suggested that the cellular subtype represents in fact congenital infantile fibrosarcoma. Cellular mesoblastic nephromas demonstrate infiltrative growth that extends into the renal pelvis (, 1). The most common clinical presentation is a palpable abdominal mass, with hematuria occurring less frequently. At imaging, mesoblastic nephroma appears as a unicentric, relatively homogeneous, solid mass that typically involves the renal.

Wilms tumor is the most common form of kidney cancer in children. It is also called nephroblastoma. Nephro means kidney, and a blastoma is a tumor made of embryonic tissue that has not yet fully developed. Accounting for 7% of children's cancer cases, approximately 500 children are diagnosed with Wilms tumor in the United States each year. The ICC panel for this group includes WT1, bcl2, vimentin and desmin.31 WT1 is uniformly positive in the primitive undifferentiated stromal component in Wilms' tumour and negative in the differentiated stromal elements of Wilms' tumours, cellular mesoblastic nephroma (except for rare cases), CCSK and synovial sarcomas.31 Bcl-2 is positive. Type 1 Excludes Crosswalk. Type 2 Excludes Crosswalk. Use Additional Crosswalk. Changes. ICD-10-CM. New 2021 Codes. Codes Revised in 2021. Codes Deleted in 2021. ICD-10-PCS The ability of infantile hypercalcemic tumors (three rhabdoid renal tumors, one cellular mesoblastic nephroma, and one hepatoblastoma) to produce parathyroid hormone (PTH) was tested using RNADNA hybridization. Results were compared with those obtained in one lung epidermoid carcinoma and one parathyroid adenoma from adult patients. Elevated plasma immunoreactive PTH (iPTH) concentrations were. Activating neurotrophic receptor kinase (NTRK) fusions define certain pediatric mesenchymal tumors, including infantile fibrosarcoma and cellular mesoblastic nephroma.Traditionally, molecular confirmation of these fusions has included either fluorescent in situ hybridization for ETV6 rearrangements or reverse-transcriptase polymerase chain reaction for the classic ETV6-NTRK3 fusion

Congenital mesoblastic nephroma: treatment options

Mesoblastic nephroma (MN) is the most common renal tumor diagnosed in infancy. A case of congenital MN was diagnosed in a 6‐month old child by fine‐needle aspiration cytology. The smears were cellular and consisted of plump spindle cells arranged in clusters along with scattered naked nuclei in the background. Blastemal, epithelial, or glomeruloid structures were not seen. Considering the. Correct. Answer: Rhabdoid tumor of the kidney. Histology: This is a sheet like proliferation of monotonous cells featuring vesicular chromatin, prominent nucleoli, and hyaline cytoplasmic inclusions. The lesion is highly invasive, as it engulfs native glomeruli and invades nerves. A high mitotic rate and necrosis are evident Cellular mesoblastic nephroma can be mistaken for Wilms tumor. WT1 does not stain mesoblastic nephroma. Unlike Wilms tumor, malignant rhabdoid tumor shows prominent nucleoli and cytoplasmic inclusions. While WT1 is negative in rhabdoid tumors, they also characteristically show lack of nuclear staining for BAF47 (INI1)

Cellular mesoblastic nephroma in an infant: Report of the

cellular mesoblastic nephroma benign fibrous histiocytoma (BFH) solitary fibrous tumor (SFT) synovial sarcoma mesenchymal chondrosarcoma leiomyosarcomas endometrial stromal sarcoma congenital fibrosarcoma. References. Gengler C, Guillou L. Solitary fibrous tumour and haemangiopericytoma: evolution of a concept. Histopathology. 2006 Jan;48(1):63-74 and cellular. We present a 32-week gestation infant and his histopathology reports of cellular CMN presented with refractory hypertension. Key words: hypertension, newborn, mesoblastic nephroma. Congenital Mesoblastic Nephroma (CMN) is a rare renal tumor in childhood. It frequently presents within the first si We report the development of a reverse transcriptase polymerase chain reaction assay that reliably detects the ETV6-NTRK3 chimeric RNA characteristic of infantile fibrosarcoma and the cellular variant of congenital mesoblastic nephroma (CMN) in formalin-fixed, paraffin-embedded tissue blocks Developed by renowned radiologists in each specialty, STATdx provides comprehensive decision support you can rely on - Mesoblastic Nephroma We conclude that a combination of WT-1 and Bcl-2 immunohistochemistry may aid in the distinction of stromal Wilms tumor, monophasic synovial sarcoma, cellular mesoblastic nephroma, and CCSK. AB - The confident diagnosis of renal spindle cell tumors in children is often difficult

Management of mixed type congenital mesoblastic nephroma